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Two years have passed since we left Daniele and the ship of madmen. Many things have changed: Daniele and Nina have become the parents of little Maria and shortly after her birth they separated. We find them fighting for custody of the little girl with the support of their respective, very different families. Daniele, after the intense experience he had during the CHT week, has...。★取材自西班牙骇人实验新闻。 ★打破西语系鬼片票房纪录。 「清醒比睡著更容易撞见鬼」研究指出；长期不睡觉，思维会错乱。精神游走在一种半剥离的灵界状态，容易看到根本不存在的东西。 1980年代，性格古怪的实验家-艾玛，喜欢挑战人体极限。她的最新实验是进行长时间不阖眼，观察知觉达到临界点的变化；她们选在废弃的精神病医院裡进行实验，众人透过排练舞台剧保持清醒状态。 碧昂卡是新位掘起的女演员，为了更多曝光机会，也参与实验，但不知名的力量在医院中扩散，悄悄地将众人推向幽暗的悲剧…。